The types of injuries most commonly treated by Regenexx procedures include fractures that have failed to heal, joint cartilage problems, chronic bursitis, avascular necrosis of the bone, lumbar disc bulges, and partial tears of tendons, muscles, or ligaments.
No. All Regenexx procedures contain a concentrate drawn from bone marrow in your iliac crest (hip). Research has shown that drawing from bone marrow (mesenchymal) is the most effective in healing orthopedic injuries.
Regenexx procedures are much less risky than typical surgical procedures because Regenexx procedures are minimally invasive and do not require general anesthesia. Surgical procedures carry a serious risk of complications or even death.
The Regenexx procedures are unique. They use many proprietary, innovative techniques to maximize the bone marrow concentrate and to ensure delivery and growth of those cells. See the Regenexx Difference for more information.
All of the Regenexx procedures performed in the United States today are FDA compliant. These same-day procedures comply with CFR 21 Part 1271, falling under the same surgery exemption discussed in 1271.15 (b).
There is some common confusion about FDA approval of Regenexx as a result of reports about our case against the FDA for the last few years. That case relates only to the Regenexx C procedure, which is different from any Regenexx procedures now being performed in the United States.
Our providers will look at your medical records and imagery and will speak with you about whether Regenexx procedures may help your problem.
We prefer CDs rather than hard copies of actual films, but we can work with either. Most imaging centers can easily and inexpensively burn a CD with the digital copies of your films. You can request these records from your previous providers, or you can authorize us to request your records on your behalf. Records should be sent to Eastern Idaho Spine, Sports & Rehab Center. When you complete a candidate form, you will receive complete instructions regarding the review process.
The growth factors that we use in the injection site are contained in your blood platelets. We need to draw blood in order to isolate and concentrate platelets for re-injection into the site.
A total of 50-200 cc may be drawn (a few teaspoons less than half a pint). A smaller amount of blood may be drawn if you weigh less than 110 pounds.
Patients often confuse a bone marrow aspirate with a more involved and more painful bone marrow biopsy. We only perform the less complicated and much more comfortable bone marrow aspirate. Because we extensively numb the area, about eight in 10 patients say that the marrow draw is very comfortable and would do it again.
The procedure uses ultrasound-guided injection and so is about as painful as a typical shot at a doctor’s office.
The results should become apparent over one to three months, but your body continues to heal for as long as six to nine months following the injection.
Some patients will benefit from a second or even a third procedure. Our usual protocol involves one to three injection cycles. Most patients receive a single procedure.
Because our procedures supplement natural healing, early activity is strongly encouraged. Wait times are dependent on the type of procedure performed.
If there is minimal cartilage loss and in the case of a partial tendon/ligament/muscle tear, low-impact activities are encouraged immediately after the procedure. Full high-impact activities are expected within four to six weeks of the procedure.
In the case of a partial tendon/ligament/muscle tear, low-impact activities would be encouraged immediately after the procedure. Full high-impact activities would be expected at four to six weeks.
In these cases, patients are required to refrain from using the injured body part until the pain from the procedure subsides. They then can then begin slowly increasing activities over the next few weeks. This healing process typically takes one to three weeks, with normal activity resuming at about six weeks. The only exception is when there is an existing rod or plate stabilizing the fracture site—in that case, normal activity may be resumed more quickly.
Eastern Idaho Spine, Sports & Rehab Center focuses our healing efforts beyond a single injured body part to help prevent the return of the injury. As a result, it’s likely we will recommend other types of conservative care to restore normal biomechanics including physical therapy, different types of myofascial release, or specific home exercises.
The success rate depends on the severity of the injury.
What research supports the efficacy of transplanting mesenchymal stem cells (MSC) from bone marrow to heal orthopedic issues?
- bone-marrow concentrate plus fat injections help knee arthritis function
- knee surgery with concentrated bone-marrow cells produces better results than knee surgery alone
- injectable MSCs helps cartilage-repair scores in patients undergoing HTO surgery
- meniscus repair in the red-white zone
- microfracture plus bone-marrow concentrate for cartilage repair
- knee osteochondral lesion stem-cell concentrate plus HA
- concentrated bone-marrow stem cells plus microfracture better than microfracture alone
- bone-marrow concentrate plus microfracture stimulates successful cartilage repair in focal lesions…
- mesenchymal stem cells plus hyaluronic acid used with knee microfracture surgery
- bone-marrow concentrate plus bioscaffold for larger knee-cartilage lesions
- arthroscopic surgery plus bone-marrow concentrate produces better cartilage repair on MRI than control images
- cultured bone-marrow stem-cell injections indicate better quality cartilage on follow-up MRIs
- one-step bone-marrow-derived cell transplantation in talar osteochondral lesions
- knee arthritis treated with HTO and microfracture plus stem cells
- clinical studies of cartilage repair using bone-marrow concentrates and cultured bone-marrow stem cells
- osteonecrosis of the femoral head
- study on AVN of the hip
- one of the original studies on using bone-marrow stem cells for AVN of the hip (1990s)
- hip osteoarthritis
- bone-marrow stem cells dramatically improve rotator cuff healing at 10 year follow-up
- marrow-nucleated cells work as well as cultured cells for tendon repair
- equine model
- bone-marrow-nucleated cells promote PCL healing (animal model)
- bone-marrow-nucleated cells help heal MCL ligaments (animal model)
- bone-marrow concentrate improves hip-fracture healing
- bone-marrow concentrate improves sinus-surgery-implant survival rates
- bone-marrow concentrate helps non-union fractures heal
- promoting spinal fusion
- fracture healing
- fracture healing (pseudo-arthrosis)
- fracture non-union
- bone-marow stem cell stimulate healing of non-healing fractures
Building New Blood Vessels